Cefpiramide acid( —— )

Catalog No. M15715 CAS No. 70797-11-4

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HNMR

HPLC

MSDS

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Product Name

Cefpiramide acid
Note

Research use only, not for human use.
Brief Description

Cefpiramide is a third-generation cephalosporin antibiotic.
Description

Cefpiramide is a third-generation cephalosporin antibiotic.
In Vitro

Cefpiramide (0-2048 μg/mL; 16-18 hours) shows good activity to against most non-fermentative Gram-negative bacilli and Enterococci (32 μg/mL with 97% inhibition).Cefpiramide (0-2048 μg/mL; 16-18 hours) exhibits high effective to against Pseudomonas aeruginosa with MIC[50] and MIC[90] values of 4 μg/mL and 16 μg/mL separately. Cell Viability Assay Cell Line:761 bacterial isolates (35 different species of common bacterial pathogens) Concentration:0-2048 μg/mL Incubation Time:16-18 hours Result:Showed broad-spectrum antibacterial activity.
In Vivo

Cefpiramide (25 mg/kg; i.v.; once) shows anti-Streptococcus pneumoniae activity in experimental pneumococcal meningitis.Cefpiramide (25 mg/kg; i.v.; once) reduces bacteria in CSF more than 10 CFU/ml. Animal Model:New Zealand white male rabbits(2-3 kg).Dosage:25 mg/kg Administration:Intravenous injection; once.Result:Anti-Streptococcus pneumoniae.
Synonyms

——
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

PBPs
Research Area

——
Indication

——

CAS Number

70797-11-4
Formula Weight

612.64
Molecular Formula

C25H24N8O7S2
Purity

>98% (HPLC)
Solubility

Water: insoluble; DMSO: insoluble
SMILES

CC1=CC(=O)C(=CN1)C(=O)N[C@H](C2=CC=C(C=C2)O)C(=O)N[C@H]3[C@@H]4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O
Chemical Name

——

1. Fass RJ, Helsel VL. Diagn Microbiol Infect Dis. 1986 Jan;4(1):77-8

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